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            <gco:CharacterString>In 2012, Colorado experienced one of its worst wildfire seasons of the past decade. The goal of this study was to investigate the relationship of local PMâ.â levels, modeled using the Weather Research and Forecasting Model with Chemistry, with emergency department visits and acute hospitalizations for respiratory and cardiovascular outcomes during the 2012 Colorado wildfires. Conditional logistic regression was used to assess the relationship between both continuous and categorical PMâ.â and emergency department visits during the wildfire period, from June 5th to July 6th 2012. For respiratory outcomes, we observed positive relationships between lag 0 PMâ.â and asthma/wheeze (1 h max OR 1.01, 95 % CI (1.00, 1.01) per 10 Î¼g/mÂ³; 24 h mean OR 1.04 95 % CI (1.02, 1.06) per 5 Î¼g/mÂ³), and COPD (1 h max OR 1.01 95 % CI (1.00, 1.02) per 10 Î¼g/mÂ³; 24 h mean OR 1.05 95 % CI (1.02, 1.08) per 5 Î¼g/mÂ³). These associations were also positive for 2-day and 3-day moving average lag periods. When PMâ.â was modeled as a categorical variable, bronchitis also showed elevated effect estimates over the referent groups for lag 0 24 h average concentration. Cardiovascular results were consistent with no association. Conclusions We observed positive associations between PMâ.â from wildfire and respiratory diseases, supporting evidence from previous research that wildfire PMâ.â is an important source for adverse respiratory health outcomes.</gco:CharacterString>
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