edu.ucar.opensky::articles:43791 UCAR/NCAR - Library OpenSky Support PO Box 3000 Boulder CO 80307-3000 opensky@ucar.edu http://opensky.ucar.edu/ homepage pointOfContact 2025-12-24T17:47:48.905359 ISO 19115-2 Geographic Information - Metadata - Part 2: Extensions for Imagery and Gridded Data ISO 19115-2:2009(E) https://n2t.net/ark:/85065/d7z03dkj Elevated exposure to air pollutants accelerates primary glomerular disease progression 2025-06-02T00:00:00Z publication https://n2t.net/ark:/85065/d7z03dkj https://doi.org/10.1093/ckj/sfaf140 Troost, J. P. author Kshirsagar, A. V. author Engel, L. S. author O'Lenick, C. R. author Smoyer, W. E. author Klein, J. author Helmuth, M. author Mariani, L. H. author Kretzler, M. author Smith, A. R. author Lacey, Forrest author Trachtman, H. author UCAR/NCAR - Library publisher Air pollution is a global problem and a major contributor to adverse health outcomes in patients of all ages. Most research has focused on the adverse effects of air pollution on cardiopulmonary events such as myocardial infarction, stroke and lung disease, with less attention given to kidney outcomes. In recent years, there is emerging evidence that air pollution contributes to the onset and progression of chronic kidney disease and, specifically, glomerular disease. This has been confirmed in epidemiological studies performed around the world. In this review, we summarize: (i) the major sources and components of air pollution; (ii) published reports detailing the relationship between air pollution exposure and the incidence and the clinical course of chronic kidney disease; and (iii) the existing literature assessing the impact of air pollution on the progression of primary glomerular diseases. We highlight important gaps in knowledge and the need for future collaborative work involving environmental scientists, epidemiologists and nephrologists to better understand the contribution of air pollution to the increasing number of people worldwide with chronic kidney disease. This work is important because air pollution exposure represents a potentially modifiable risk factor for chronic kidney disease progression that can be addressed by regulatory action, personal behaviors and implementation of interventions to prevent or limit exposure. UCAR/NCAR - Library OpenSky Support PO Box 3000 Boulder CO 80307-3000 opensky@ucar.edu http://opensky.ucar.edu/ homepage pointOfContact PDF Text theme Resource Type 2016-01-01T00:00:00Z publication <span style="font-family:Arial;font-size:10pt;font-style:normal;" data-sheets-root="1">Copyright author(s). This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.</span> None eng geoscientificInformation